Fibroblast growth factors
نویسنده
چکیده
What are they? Fibroblast growth factors (FGFs) are a family of small (20–30 kDa) intercellular signalling proteins which are frequently found to be glycosylated. The first draft of the human genome identified 29 potential FGF genes, and so far transcripts have been identified for 23 of them. Two FGFs have been identified in Caenorhabditis elegans (Let-756 and Egl-17) while Drosophila appears only to have a single FGF gene (branchless). The identification of six FGF genes in the sea squirt, Ciona, a basal chordate, suggests that the process of gene duplication and divergence was well underway early during chordate evolution.
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ورودعنوان ژورنال:
- Current Biology
دوره 13 شماره
صفحات -
تاریخ انتشار 2003